Biofourmis to run new study, SingHEART Vitals on how Singapore’s lifestyle affects heart health

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Biofourmis aims to correlate how lifestyle affects heart health and build predictive models in detecting risk factors patients with cardiovascular diseases will face

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Biofourmis, a healthcare data analytics company, has embarked on a partnership with the National Heart Centre Singapore (NHCS) in a new study to identify the risk factors amongst people in the Singapore population who are prone to be suffering from cardiovascular diseases. The Infocomm Media Development Authority (IMDA) has collaborated with NHCS and Biofourmis to conceptualise this opportunity and is co-funding Biofourmis to kick-start this initiative.

Named as the SingHEART Vitals study, it aims to establish normal references in Singapore residents using a comprehensive array of tests including blood tests, coronary calcium score, ambulatory blood pressure, continuous electrocardiogram and fitness/activity trackers. The study which started in October 2016, involves 500 volunteers who will undergo a series of studies at baseline which also includes continuous monitoring of electrocardiograms, Blood Pressure and Activity for a period of one week and are then tracked over a five to ten year period for adverse cardiovascular outcomes.

“There has never been a similar study like this to monitor the Asian population. This partnership with NHCS will enable us to be one of the first in the world to perform sophisticated analysis and modelling to dig into the architecture of these measured vitals signs in the Singapore populace and build personalized physiological health models for people using BiovitalsTM. We are extremely privileged to be supported by IMDA in this initiative. We are constantly benefitting from IMDA’s dedicated efforts to create an ecosystem where the industry can get the exposure, knowledge and experience they require, through partnerships with relevant stakeholders,” said Mr. Kuldeep Singh Rajput, CEO of Biofourmis.

Credit: Biofourmis
Credit: Biofourmis

Commenting on the study, Associate Professor Yeo Khung Keong, Senior Consultant, Department of Cardiology, National Heart Centre Singapore said, “The study will allow us to analyse how an individual’s vital signs affect his or her heart health. We can then use this information to build predictive models to determine risk of developing heart disease. Hopefully doctors can use such research to prevent and detect early heart disease.”

The partnership will perform sophisticated analysis and modelling to understand the architecture of these measured vital signs in normal Singapore residents. These findings are important as they will provide the foundation to understand how technology, research or commercial/clinical application can be used effectively in measuring vital signs. In particular, they will be critical for technologies that hope to leverage on commercially available wearable technologies.

This collaboration will provide a substantial advantage in that we would have the benefit of having the actual data from normal patients with comprehensive correlation with other measures of health (eg. Cardiac MRI). This enables identifying risk factors for diseases and targets for preventive healthcare. The overall goal of the project is to build predictive risk models for various cardiovascular diseases in different segments of population for Singapore. There are no published data utilizing such deep and multifaceted analytics of vitals signs in normal people.

Biofourmis, with its deep expertise and experience in wearable data analytics, will have a pivotal role in the study. Volunteers who are enrolled into the study will undergo continuous electrocardiogram, blood pressure and heart rate monitoring along with activity tracking (steps, calories, distance and sleep) where data will be collected over one-week’s period using ePatch Cardiac Monitor, FitBit Charge HR and SpaceLab Ambulatory Blood Pressure.

“Data analytics is a key way in which we find opportunities in a digital future. Collaborations with local tech companies such as Biofourmis are a good example of tackling real world healthcare challenges to deepen tech capabilities that both help the local tech ecosystem as well as enable potential transformations in the healthcare sector,” said Mr Khoong Hock Yun, Assistant Chief Executive (Development), IMDA.

Mr. Rajput further added, “We intend to use the results of this study to provide the competitive advantage where we will be able to build correlation algorithms in understanding how lifestyle affects one’s health along with other health parameters – physiology. Our overall goal from this collaboration is to build predictive models and understand the parameters which influence the risk to be affected by a cardiovascular diseases in different segments of the Singapore population.”